Here, we show that conolidine, a pure analgesic alkaloid used in traditional Chinese drugs, targets ACKR3, thus providing supplemental evidence of a correlation amongst ACKR3 and pain modulation and opening substitute therapeutic avenues for the cure of chronic pain. The 1st asymmetric complete synthesis of conolidine was developed by https://alexisewqhx.blogdiloz.com/31540277/the-smart-trick-of-conolidine-that-no-one-is-discussing