Contrary to other favourable allosteric modulators that boost ligand binding, benzodiazepine binding acts for a constructive allosteric modulator by increasing the overall conduction of chloride ions across the neuronal mobile membrane when GABA is already sure to its receptor. This greater chloride ion influx hyperpolarizes the neuron's membrane potential. https://benzodiazepinespowdersfor17395.popup-blog.com/34982224/not-known-details-about-benzodiazepines-classification