Pentobarbital will decrease the level or effect of alfentanil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Minor/Significance Unknown. pentobarbital will decrease the level or effect of diclofenac by affecting hepatic enzyme CYP2C9/10 metabolism. Minor/Significance Unknown. pentobarbital decreases effects of sufentanil SL by affecting hepatic/intestinal enzyme CYP3A4 meta... https://macrobookmarks.com/story20449238/indicatori-sulla-pentobarbital-si-deve-sapere